Camacho-Zarco; Sofía Medina-Ruíz; Paul Gaytán; Mauricio Carrillo-Tripp; Vilmos Fülöp; Fr ..., Molecular Biology and Evolution, 2013 Despite the prominent role of horizontal gene transfer (HGT) in shaping bacterial metabolism, little is known about the impact of HGT on the evolution of enzyme function.
Specifically, what is the influence of a recently acquired gene on the function of an existing gene? more Predicting protein‐DNA interactions by full search computational docking 22-Aug-2013 | Victoria A. Ten Eyck, Sheng Li, Proteins: Structure, Function, and Bioinformatics, 2013 Abstract Protein‐DNA interactions are essential for many biological processes, X‐ray crystallography can provide high‐resolution structures, but protein‐DNA complexes are difficult to crystallize and typically contain only small DNA fragments.
3.5Å cryo EM Structure of Hepatitis B Virus Core Assembled from Full-Length Core Protein 06-Sep-2013 | Xuekui Yu et al., PLo S ONE, 2013 by Xuekui Yu, Lei Jin, Jonathan Jih, Chiaho Shih, Z.
Hong Zhou The capsid shell of infectious hepatitis B virus (HBV) is composed of 240 copies of a single protein called HBV core antigen (HBc).
An atomic model of a core assembled from truncated HBc was determined previously by X-ray ...
more Evolution of Substrate Specificity in a Recipient’s Enzyme Following Horizontal Gene Transfer 01-Sep-2013 | Lianet Noda-García; Aldo R.
X-ray diffraction is now a common technique for the study of crystal structures and atomic spacing.
X-ray diffraction is based on constructive interference of monochromatic X-rays and a crystalline sample.
Powder and single crystal diffraction vary in instrumentation beyond this.
X-rays are generated in a cathode ray tube by heating a filament to produce electrons, accelerating the electrons toward a target by applying a voltage, and bombarding the target material with electrons.